Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2004 Aug;145(2):259-62.
doi: 10.1016/j.jpeds.2004.05.033.

Nitric oxide synthesis in ornithine transcarbamylase deficiency: possible involvement of low no synthesis in clinical manifestations of urea cycle defect

Hironori Nagasaka  1 , Haruki Komatsu, Toshihiro Ohura, Tsuyoshi Sogo, Ayano Inui, Tohru Yorifuji, Kei Murayama, Masaki Takayanagi, Hideaki Kikuta, Kunihiko Kobayashi
Affiliations

Nitric oxide synthesis in ornithine transcarbamylase deficiency: possible involvement of low no synthesis in clinical manifestations of urea cycle defect

Hironori Nagasaka et al. J Pediatr. 2004 Aug.

Abstract

Nitric oxide (NO) levels in plasma and urine were determined in 5 girls with ornithine transcarbamylase deficiency (OTCD) of late-onset type, who often developed migraine-like headache or vomiting. The patients were found to have low NO synthesis, suggesting that the low NO synthesis contributes to the clinical manifestations of urea cycle defect.

PubMed Disclaimer