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Review
. 2004 Aug;145(2):273-6.
doi: 10.1016/j.jpeds.2004.05.027.

Acute vanishing bile duct syndrome after ibuprofen therapy in a child

M Taghian  1 , T A Tran, S Bresson-Hadni, A Menget, S Felix, E Jacquemin
Affiliations
Review

Acute vanishing bile duct syndrome after ibuprofen therapy in a child

M Taghian et al. J Pediatr. 2004 Aug.

Abstract

We report the case of a 10 year-old girl who had Stevens-Johnson syndrome and cholestasis after ibuprofen therapy. Liver histology was compatible with vanishing bile duct syndrome. She received ursodeoxycholic acid, and liver tests normalized within 7 months. This report confirms that ibuprofen may induce acute vanishing bile duct syndrome.

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