[A prospective study on the risk factors of Acinetobacter banmannii bacteremia infection in incubated patients with nosocomial pneumonia]

Abstract

Objective: To study the epidemiology of Acinetobacter baumannii infection in patients with ventilator-associated pneumonia (VAP).

Methods: Prospective clinical study was carried out with 176 episodes of VAP with etiologic diagnosis being followed in two groups.

Results: Twenty-six episodes were caused by Acinetobacter baumannii and one hundred-fifty episodes were caused by "other" organisms. Using logistic regression analysis, the risk of VAP due to Acinetobacter baumannii was found to be high in patients with head trauma [odds ratio (OR) = 4.20, 95% confidence interva (CI): 2.72 to 6.48], surgery (OR = 2.88, 95% CI: 1.78 to 4.66), acute respiratory dispnea syndrome (OR = 2.81, 95% CI: 1.19 to 6.64), and large-volume pulmonary aspiration (OR = 6.71, 95% CI: 3.91 to 11.50).

Conclusions: Acinetobacter baumannii pulmonary infection in incubated patients had an epidemiological pattern that different from "other" organisms. Patients with high risk identified in our study might mark the existence of cross-infection during airway manipulation.