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Review
. 2004 Sep;18(3):467-511, viii.
doi: 10.1016/j.idc.2004.04.003.

Pathogens resistant to antimicrobial agents: epidemiology, molecular mechanisms, and clinical management

Keith S Kaye  1 , John J Engemann, Henry S Fraimow, Elias Abrutyn
Affiliations
Review

Pathogens resistant to antimicrobial agents: epidemiology, molecular mechanisms, and clinical management

Keith S Kaye et al. Infect Dis Clin North Am. 2004 Sep.

Abstract

Resistance to antimicrobial drugs is increasing at an alarming rate among both gram-positive and gram-negative bacteria. Traditionally, bacteria resistant to multiple antimicrobial agents have been restricted to the nosocomial environment. A disturbing trend has been the recent emergence and spread of resistant pathogens and resistance traits in nursing homes, the community, as well as in hospitals. This article reviews the epidemiology, molecular mechanisms of resistance, and treatment options for pathogens resistant to antimicrobial drugs.

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