The newer fluoroquinolones
- PMID: 15308282
- DOI: 10.1016/j.idc.2004.04.011
The newer fluoroquinolones
Abstract
This article discusses the newer fluoroquinolones in detail with respect to their pharmacokinetics, pharmacodynamics, safety, and spectrum of in vitro activity. The newer agents are compared and contrasted with the older ones, particularly ciprofloxacin. Efficacy of the newer fluoroquinolones when compared with antimicrobial agents in other classes is also presented in detail. Appropriate use of the newer fluoroquinolones is addressed, including their ever expanding role in the treatment of both upper and lower respiratory tract infections and skin and soft tissue infection. Available data on the use of the newer fluoroquinolones in the management of genitourinary tract infections, gastrointestinal infections, and osteomyelitis are also discussed.
Similar articles
-
Fluoroquinolones.Infect Dis Clin North Am. 2000 Jun;14(2):489-513, xi. doi: 10.1016/s0891-5520(05)70260-9. Infect Dis Clin North Am. 2000. PMID: 10829268 Review.
-
The quinolones: decades of development and use.J Antimicrob Chemother. 2003 May;51 Suppl 1:13-20. doi: 10.1093/jac/dkg208. J Antimicrob Chemother. 2003. PMID: 12702699 Review.
-
Fluoroquinolones: mechanism of action, classification, and development of resistance.Surv Ophthalmol. 2004 Mar;49 Suppl 2:S73-8. doi: 10.1016/j.survophthal.2004.01.005. Surv Ophthalmol. 2004. PMID: 15028482 Review.
-
[New fluoroquinolones in urology].Urologiia. 2004 Jul-Aug;(4):27-32. Urologiia. 2004. PMID: 15457949 Review. Russian.
-
Fluoroquinolones and anaerobes.Clin Infect Dis. 2006 Jun 1;42(11):1598-607. doi: 10.1086/503907. Epub 2006 Apr 24. Clin Infect Dis. 2006. PMID: 16652318 Review.
Cited by
-
Synthesis of 1,2,3-Triazolo[4,5-h]quinolone Derivatives with Novel Anti-Microbial Properties against Metronidazole Resistant Helicobacter pylori.Molecules. 2017 May 20;22(5):841. doi: 10.3390/molecules22050841. Molecules. 2017. PMID: 28531095 Free PMC article.
-
Pharmacokinetics of Enrofloxacin in Plasma, Urine, and Feces of Donkey (Equus asinus) after a Single Intragastric Administration.Antibiotics (Basel). 2024 Apr 12;13(4):355. doi: 10.3390/antibiotics13040355. Antibiotics (Basel). 2024. PMID: 38667031 Free PMC article.
-
The Rise, Fall, and Rethink of (Fluoro)quinolones: A Quick Rundown.Pathogens. 2025 May 24;14(6):525. doi: 10.3390/pathogens14060525. Pathogens. 2025. PMID: 40559533 Free PMC article. Review.
-
Levofloxacin-induced Achilles tendinitis in a young adult in the absence of predisposing conditions.Yonsei Med J. 2010 May;51(3):454-6. doi: 10.3349/ymj.2010.51.3.454. Yonsei Med J. 2010. PMID: 20376902 Free PMC article.
-
Fluoroquinolone susceptibility in Mycobacterium tuberculosis after pre-diagnosis exposure to older- versus newer-generation fluoroquinolones.Int J Antimicrob Agents. 2013 Sep;42(3):232-7. doi: 10.1016/j.ijantimicag.2013.04.027. Epub 2013 Jun 24. Int J Antimicrob Agents. 2013. PMID: 23806638 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
