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Comment
. 2004 Aug;8(4):222-6.
doi: 10.1186/cc2917. Epub 2004 Jul 9.

Severe sepsis epidemiology: sampling, selection, and society

Walter T Linde-Zwirble  1 , Derek C Angus
Affiliations
Comment

Severe sepsis epidemiology: sampling, selection, and society

Walter T Linde-Zwirble et al. Crit Care. 2004 Aug.

Abstract

Three new articles in Critical Care add to an expanding body of information on the epidemiology of severe sepsis. Although there have been a range of approaches to estimate the incidence of severe sepsis, most studies report severe sepsis in about 10 +/- 4% of ICU patients with a population incidence of 1 +/- 0.5 cases per 1000. Importantly, the availability of ICU services may well determine the number of treated cases of severe sepsis, and it seems clear that these studies are reporting the treated incidence, not the incidence, of severe sepsis. In the future, we must focus on whether all severe sepsis should be treated, and, consequently, what level of ICU services is optimal.

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Comment on

  • Prevalence and incidence of severe sepsis in Dutch intensive care units.
    van Gestel A, Bakker J, Veraart CP, van Hout BA. van Gestel A, et al. Crit Care. 2004 Aug;8(4):R153-62. doi: 10.1186/cc2858. Epub 2004 May 14. Crit Care. 2004. PMID: 15312213 Free PMC article.
  • Epidemiology of sepsis in Norway in 1999.
    Flaatten H. Flaatten H. Crit Care. 2004 Aug;8(4):R180-4. doi: 10.1186/cc2867. Epub 2004 May 14. Crit Care. 2004. PMID: 15312216 Free PMC article.
  • Brazilian Sepsis Epidemiological Study (BASES study).
    Silva E, Pedro Mde A, Sogayar AC, Mohovic T, Silva CL, Janiszewski M, Cal RG, de Sousa EF, Abe TP, de Andrade J, de Matos JD, Rezende E, Assunção M, Avezum A, Rocha PC, de Matos GF, Bento AM, Corrêa AD, Vieira PC, Knobel E; Brazilian Sepsis Epidemiological Study. Silva E, et al. Crit Care. 2004 Aug;8(4):R251-60. doi: 10.1186/cc2892. Epub 2004 Jun 15. Crit Care. 2004. PMID: 15312226 Free PMC article.

References

    1. Anonymous American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med. 1992;20:864–874. - PubMed
    1. Slade E, Tamber PS, Vincent JL. The Surviving Sepsis Campaign: raising awareness to reduce mortality. Crit Care. 2003;7:1–2. doi: 10.1186/cc1876. - DOI - PMC - PubMed
    1. Dellinger RP, Carlet JM, Masur H, Gerlach H, Calandra T, Cohen J, Gea-Banacloche J, Keh D, Marshall JC, Parker MM, et al. Surviving sepsis campaign guidelines for management of severe sepsis and septic shock. Crit Care Med. 2004;32:858–873. doi: 10.1097/01.CCM.0000117317.18092.E4. - DOI - PubMed
    1. Dellinger RP, Carlet JM, Masur H, Gerlach H, Calandra T, Cohen J, Gea-Banacloche J, Keh D, Marshall JC, Parker MM, et al. Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock. Intensive Care Med. 2004;30:536–555. doi: 10.1007/s00134-004-2210-z. - DOI - PubMed
    1. Silva E, de Almeida Pedro M, Sogayar ACB, Mohovic T, de Oliveira Silva CL, Janiszewski M, Rodrigues Cal RG, de Sousa EF, Abe TP, de Andrade J, et al. Brazilian Sepsis Epidemiological Study (BASES study) Crit Care. 2004;8:R251–R260. doi: 10.1186/cc2892. - DOI - PMC - PubMed