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Review
. 2004 Aug 19;43(4):441-2.
doi: 10.1016/j.neuron.2004.08.007.

Neuropeptide S: a novel activating anxiolytic?

George F Koob  1 , Thomas N Greenwell
Affiliations
Free article
Review

Neuropeptide S: a novel activating anxiolytic?

George F Koob et al. Neuron. .
Free article

Abstract

Many different neuropharmacological agents modulate arousal and anxiety, yet to date, few endogenous substances have produced arousal with an anxiolytic effect. In this issue of Neuron, Xu et al. describe the localization and characterization of a novel neuropeptide, neuropeptide S (and its cognate receptor), that is unique in its arousing and anxiolytic-like properties.

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