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Review
. 2004 Oct;34(2):163-70.
doi: 10.1016/j.ymeth.2004.04.002.

Intrabodies as therapeutic agents

Roland E Kontermann  1
Affiliations
Review

Intrabodies as therapeutic agents

Roland E Kontermann. Methods. 2004 Oct.

Abstract

In the past decade, a large number of intracellular antibodies (intrabodies) have been developed for potential use as therapeutic agents. As antibodies can be generated against virtually any target antigen, the applications of intrabodies span a wide range including tumour therapy, infectious diseases, transplantation, and other diseases associated with protein overexpression or mutagenesis. This article summarises the development of intrabodies and their applications as therapeutic agents.

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