[Prevention of nosocomial infections in newborns at artificial lung ventilation]

Abstract

Nosocomial infections in perinatology are the leading factor affecting both the clinical course and outcome of the main disease in newborns with the artificial lung ventilation management (ALV). We undertook controllable randomized examinations of 161 newborns with ALV receiving different immunotherapy schemes for the purpose of assessing the effects of different immunotherapy methods inducing the onset and progression of the above complications. We also analyzed the clinical-and-immunologic efficiency of the suggested immunotherapy schemes in respect to a variety of the most important indices; it showed an obvious advantage of the intravenous immunoglobulin administration in doses exceeding the routine ones as well as of using the plasma cryoprecipitate for the purpose of preventing the in-hospital infections in newborns.