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. 1977 Apr 22;196(4288):440-1.
doi: 10.1126/science.15317.

Tris buffer attenuates acetylcholine responses in Aplysia neurons

Tris buffer attenuates acetylcholine responses in Aplysia neurons

W A Wilson et al. Science. .

Abstract

The commonly used buffering agent tris(hydroxymethyl)methylamine (tris) antagonizes the action of iontophoretically applied acetylcholine on neurons of Aplysia californica. Concentrations of 5 to 10 millimolar tris markedly reduced both excitatory and inhibitory responses.

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