Postactivation potentiation in human muscle is not related to the type of maximal conditioning contraction

Abstract

The mechanical performance of a muscle can be enhanced by preceding contractile activity, such as occurs with postactivation potentiation. To investigate whether the type of contraction influences the extent of potentiation, the effects of 6-s maximal isometric (ISO), concentric (CON), and eccentric (ECC) maximal voluntary contractions (MVC) on the muscle twitch were compared in the tibialis anterior of nine subjects. The study also examined the effect of postactivation potentiation on the force evoked by the second (C2) and third (C3) responses of two-pulse (PT2) and three-pulse (PT3) trains that were delivered at a 10-ms interpulse interval. The results showed that immediately after the conditioning MVC, twitch torque (Pt) and its maximal rate of torque development (+dPt/dt) and relaxation (-dPt/dt) were significantly enhanced, without any change in contraction time (CT), half-relaxation time ((1/2)RT), and compound muscle action potential (M wave). The extent of Pt potentiation was similar for all MVC modalities, and the mean maximal values ranged from 150% to 180%. Furthermore, postactivation potentiation was greater for the single pulse compared with PT2 and PT3 responses. All parameters returned to initial values within 7-10 min. Although Pt (or C1) was potentiated more than was C2 and C3, its decline over time was proportionally more rapid than those for C2 and C3. We conclude that postactivation potentiation was not related to the type of conditioning MVC under these experimental conditions. The observation that postactivation potentiation increased C1 more than C2 and C3 indicates that a saturation process limits the extent of potentiation during the summation of successive responses to a train of stimuli. These results have practical application in the design of functional electrical stimulation protocols.