Simulating genetic networks made easy: network construction with simple building blocks
- PMID: 15319258
- DOI: 10.1093/bioinformatics/bth478
Simulating genetic networks made easy: network construction with simple building blocks
Abstract
We present SIM-plex, a genetic network simulator with a very intuitive interface in which a user can easily specify interactions as simple 'if-then' statements. The simulator is based on the mathematical model of Piecewise Linear Differential Equations (PLDEs). With PLDEs, genetic interactions are approximated as acting in a switch-like manner.
Availability: The Java program, examples and a tutorial are available at http://www.psb.ugent.be/cbd/
Contact: {stcru,makui}@psb.ugent.be
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