Genomic segmental polymorphisms in inbred mouse strains
- PMID: 15322544
- DOI: 10.1038/ng1417
Genomic segmental polymorphisms in inbred mouse strains
Abstract
By analyzing genomic copy-number differences using high-resolution mouse whole-genome BAC arrays, we uncover substantial differences in regional DNA content between inbred strains of mice. The identification of these apparently common segmental polymorphisms suggests that these differences can contribute to genetic variability and pathologic susceptibility.
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