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. 2004 Jun;57(6):373-8.
doi: 10.7164/antibiotics.57.373.

Mutactimycin PR, a new anthracycline antibiotic from Saccharothrix sp. SA 103. II. Physico-chemical properties and structure elucidation

Abdelghani Zitouni  1 , Florence Mathieu, Yannick Coppel, Frederic Pont, Nasserdine Sabaou, Ahmed Lebrihi
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Free article

Mutactimycin PR, a new anthracycline antibiotic from Saccharothrix sp. SA 103. II. Physico-chemical properties and structure elucidation

Abdelghani Zitouni et al. J Antibiot (Tokyo). 2004 Jun.
Free article

Abstract

A new antibiotic termed mutactimycin PR (1) was isolated along with the known mutactimycin C (2) from the fermentation broth of Saccharothrix sp. SA 103. The two compounds belong to the anthracycline group. The structure of these antibiotics was elucidated with the aid of NMR and mass spectrometric investigations. The novel compound mutactimycin PR was characterized as 5,12 Naphtacenedione, 7-[(6-deoxy-3-O-methyl-alpha-L-mannopyranosyl)oxy]-4-[(6-deoxy-alpha-L-mannopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9 methyl.

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