Controversies in the treatment of meconium aspiration syndrome

Abstract

MAS remains an infrequent but challenging condition confronting neonatologists. Avoidance of postterm pregnancies, improved intrapartum monitoring,and amnioinfusion have been beneficial. Studies have not demonstrated conclusively that any form of ventilation is superior to others, but strategies that recruit alveoli are desirable. Surfactant lavage or replacement may be beneficial. When hypoxic respiratory failure progresses, iNO may improve oxygenation and avoid ECMO.