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Case Reports
. 2004 Aug 24;63(4):730-2.
doi: 10.1212/01.wnl.0000134606.50529.c7.

Sustained remission of CIDP associated with Evans syndrome

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Case Reports

Sustained remission of CIDP associated with Evans syndrome

Hans Knecht et al. Neurology. .

Abstract

A patient with chronic inflammatory demyelinating polyneuropathy (CIDP) developed Evans syndrome (hemolytic anemia/thrombocytopenia) 17 months after onset of symptoms despite different immunomodulatory treatments. A therapeutic approach with the chimeric monoclonal anti-CD20 antibody rituximab induced substantial improvement of CIDP and hematologic recovery. The patient remains in sustained remission 17 months after completion of therapy. Rituximab may represent a successful therapy in otherwise refractory CIDP.

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