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. 2004 Sep;50(9):1683-6.

doi: 10.1373/clinchem.2004.035436.

ACE2 gene polymorphisms do not affect outcome of severe acute respiratory syndrome

Rossa W K Chiu¹, Nelson L S Tang, David S C Hui, Grace T Y Chung, Stephen S C Chim, K C Allen Chan, Ying-man Sung, Louis Y S Chan, Yu-kwan Tong, Wing-shan Lee, Paul K S Chan, Y M Dennis Lo

Affiliations

PMID: 15331509
PMCID: PMC7108155
DOI: 10.1373/clinchem.2004.035436

ACE2 gene polymorphisms do not affect outcome of severe acute respiratory syndrome

Rossa W K Chiu et al. Clin Chem. 2004 Sep.

. 2004 Sep;50(9):1683-6.

doi: 10.1373/clinchem.2004.035436.

Authors

Rossa W K Chiu¹, Nelson L S Tang, David S C Hui, Grace T Y Chung, Stephen S C Chim, K C Allen Chan, Ying-man Sung, Louis Y S Chan, Yu-kwan Tong, Wing-shan Lee, Paul K S Chan, Y M Dennis Lo

Affiliation

¹ The Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Shatin.

PMID: 15331509
PMCID: PMC7108155
DOI: 10.1373/clinchem.2004.035436

No abstract available

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Figures

Figure 1. — Figure 1.
Schematic illustration of the genomic organization of ACE2 and positions of the studied SNP loci. ACE2 contains 18 exons. Each exon is represented by an open box. The arrows mark the positions of the five verified SNPs. All five SNPs are located within noncoding regions of ACE2. The individual SNPs are named according to their identification numbers registered at the SNP database (dbSNP) (15).

See this image and copyright information in PMC

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References

1. Peiris JS, Yuen KY, Osterhaus AD, Stohr K. The severe acute respiratory syndrome. N Engl J Med 2003;349:2431-2441. - PubMed
1. World Health Organization. Cumulative number of reported probable cases of SARS. http://www.who.int/csr/sars/country/2003_07_11/en/ (accessed May 2004)..
1. Karlberg J, Chong DS, Lai WY. Do men have a higher case fatality rate of severe acute respiratory syndrome than women do?. Am J Epidemiol 2004;159:229-231. - PMC - PubMed
1. Lee N, Hui D, Wu A, Chan P, Cameron P, Joynt GM, et al. A major outbreak of severe acute respiratory syndrome in Hong Kong. N Engl J Med 2003;348:1986-1994. - PubMed
1. Booth CM, Matukas LM, Tomlinson GA, Rachlis AR, Rose DB, Dwosh HA, et al. Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area. JAMA 2003;289:2801-2809. - PubMed

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