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Case Reports
. 1992 Mar;31(3):199-200.
doi: 10.1111/j.1365-4362.1992.tb03936.x.

Facial pyogenic granuloma-like lesions under isotretinoin therapy

J Hagler  1 , E Hodak, M David, M Sandbank
Affiliations
Case Reports

Facial pyogenic granuloma-like lesions under isotretinoin therapy

J Hagler et al. Int J Dermatol. 1992 Mar.

Abstract

A male patient with severe cystic acne was treated with 13-cis-retinoic acid in a dosage of 1 mg/kg/day. Early flare-up of his acne and multiple pyogenic-like lesions on his face appeared during the second week of isotretinoin treatment. Histologic study of the lesions revealed granulation tissue. Possible etiologies for this phenomenon are discussed.

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