Combinatorial control of gene expression
- PMID: 15332082
- DOI: 10.1038/nsmb820
Combinatorial control of gene expression
Abstract
Revealing the molecular principles of eukaryotic transcription factor assembly on specific DNA sites is pivotal to understanding how genes are differentially expressed. By analyzing structures of transcription factor complexes bound to specific DNA elements we demonstrate how protein and DNA regulators manage gene expression in a combinatorial fashion.
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