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. 1992 May;174(9):3092-4.
doi: 10.1128/jb.174.9.3092-3094.1992.

The arsenical ATPase efflux pump mediates tellurite resistance

R J Turner  1 , Y Hou, J H Weiner, D E Taylor
Affiliations

The arsenical ATPase efflux pump mediates tellurite resistance

R J Turner et al. J Bacteriol. 1992 May.

Abstract

The ars operon of the resistance plasmid R773 was found to produce moderate levels of resistance to tellurite. A MIC of 64 micrograms of TeO3(2-) per ml was found for Escherichia coli cells harboring plasmids which contained all three of the structural genes (arsA, arsB, and arsC) of the anion-translocating ATPase. MICs specified by plasmids carrying only one or two structural elements or the cloning vector alone were 2 to 4 micrograms/ml. The rate of TeO3(2-) uptake was found to be on the order of 55% less for cultures containing the resistance plasmids.

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