Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1992 Apr;29(4):239-42.
doi: 10.1136/jmg.29.4.239.

Age at onset and life table risks in genetic counselling for Huntington's disease

P S Harper  1 , R G Newcombe
Affiliations

Age at onset and life table risks in genetic counselling for Huntington's disease

P S Harper et al. J Med Genet. 1992 Apr.

Abstract

Age related genetic risk data for carrying the gene for Huntington's disease in relatives at risk, based on a previously documented life table approach, are presented in a form allowing ready access for use in genetic counselling. Figures are given for first degree relatives and for second degree relatives showing varying age combinations of consultand and intervening parent at risk. Data are also given for the risk of developing Huntington's disease over varying finite periods in relation to age. The availability of this information in tabular form should help those involved in genetic counselling for this disorder in providing accurate risk estimates to relatives; the data are also of importance for combination with genotype information in predictive testing.

PubMed Disclaimer

References

    1. Mov Disord. 1990;5(2):93-9 - PubMed
    1. Clin Genet. 1990 Sep;38(3):180-6 - PubMed
    1. Lancet. 1989 Sep 9;2(8663):601-3 - PubMed
    1. Clin Genet. 1985 Aug;28(2):100-5 - PubMed
    1. Am J Hum Genet. 1988 Nov;43(5):695-704 - PubMed