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Clinical Trial
. 2004 May;2(3):182-4.
doi: 10.3736/jcim20040309.

[Influence of Jieyu Huoxue Decoction on rehabilitation of patients with depression after cerebral infarction]

[Article in Chinese]
Bei-Lei Feng  1 , Qiao-Chu Wang, Zheng-Yuan Li
Affiliations
Clinical Trial

[Influence of Jieyu Huoxue Decoction on rehabilitation of patients with depression after cerebral infarction]

[Article in Chinese]
Bei-Lei Feng et al. Zhong Xi Yi Jie He Xue Bao. 2004 May.

Erratum in

  • Zhong Xi Yi Jie He Xue Bao. 2005 Jan;3(1):34

Abstract

Objective: To study the influence of Jieyu Huoxue Decoction on rehabilitation of patients with depression after cerebral infarction.

Methods: Fifty four patients suffered from the depression after acute cerebral infarction were randomly divided into three groups: depression control group, fluoxetine treated group and Jieyu Huoxue Decoction treated group. Eighteen patients of cerebral infarction without depression were enrolled in the no depression control group randomly. The Zung self-rating depression scale (SDS), the modified Edinburgh-Scandinavia stroke scale (MESSS) and the activities of daily living (ADL) were evaluated before treatment, 30 and 60 days after treatment.

Results: After 30 and 60 days of treatment, SDS evaluation of the Jieyu Huoxue Decoction treated group showed significant difference as compared with the condition before treatment and that of the depression control group (P < 0.05 or P < 0.01), MESSS evaluation and ADL evaluation also showed significant difference as compared with the condition before treatment and that of the depression control group (P < 0.05 or P < 0.01); there was no obvious difference between the fluoxetine treated group and the Jieyu Huoxue Decoction treated group, but the Jieyu Huoxue Decoction treated group showed fewer symptoms and less side effect.

Conclusion: Jieyu Huoxue Decoction can not only relieve depression after cerebral infarction, but also improve neurological functions.

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