Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 2004 Jan;2(1):17-9.
doi: 10.3736/jcim20040107.

[Effect of kidney-warming and astringent therapy on plasma endothelin and interleukin-2 receptor in patients with nephrotic syndrome]

[Article in Chinese]
Hui Lu  1 , Yan-Yan Wang, Mei-Zhu Guo, Chun-Li Wang
Affiliations
Clinical Trial

[Effect of kidney-warming and astringent therapy on plasma endothelin and interleukin-2 receptor in patients with nephrotic syndrome]

[Article in Chinese]
Hui Lu et al. Zhong Xi Yi Jie He Xue Bao. 2004 Jan.

Abstract

Objective: To explore the effect and mechanism of kidney-warming and astringent therapy in treating nephrotic syndrome patients with deficiency of spleen and kidney yang and overflow of water, and to observe the change of plasma endothelin and interleukin-2 receptor after treatment.

Methods: Forty-four patients were randomly divided into conventional steroid treated group (control group, 20 cases) and conventional steroid plus kidney-warming and astringent therapy treated group (treatment group, 24 cases). The levels of plasma endothelin (ET) and soluble interleukin-2 receptor (sIL-2) were observed.

Results: Before treatment, plasma ET and sIL-2 in the patients were significantly higher than those in healthy people (P<0.01). After treatment, the ET and sIL-2 levels were obviously improved in both treated groups (P<0.05) and the improvement in the treatment group was more obvious. The difference between the two treated groups after treatment was significant (P<0.05).

Conclusion: Conventional treatment plus kidney-warming and astringent therapy can effectively improve the levels of plasma ET and sIL-2 in treating nephrotic syndrome patients with deficiency of spleen and kidney yang and overflow of water, and hence alleviate the damage of renal tissue.

PubMed Disclaimer