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Review
. 2004 Sep 2;43(5):596-9.
doi: 10.1016/j.neuron.2004.08.025.

Food for thought: essential fatty acid protects against neuronal deficits in transgenic mouse model of AD

Lennart Mucke  1 , Robert E Pitas
Affiliations
Free article
Review

Food for thought: essential fatty acid protects against neuronal deficits in transgenic mouse model of AD

Lennart Mucke et al. Neuron. .
Free article

Abstract

Interactions between environmental and genetic factors may contribute to neurodegenerative disease. In this issue of Neuron, Calon et al. report that a diet low in an essential omega-3 polyunsaturated fatty acid (docosahexaenoic acid) depletes postsynaptic proteins and exacerbates behavioral alterations in a transgenic mouse model of Alzheimer's disease.

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