Membrane targeting: glued by a lipid to the ER
- PMID: 15341762
- DOI: 10.1016/j.cub.2004.08.045
Membrane targeting: glued by a lipid to the ER
Abstract
Opi1p, a transcription regulator of phospholipid metabolism in budding yeast, is retained in the endoplasmic reticulum by association with Scs2p. New research shows that binding of phosphatidic acid to Opi1p is a prerequisite for this targeting.
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