Review
doi: 10.1016/j.cub.2004.08.048.
Tumor metastasis: a new twist on epithelial-mesenchymal transitions
Affiliations
- PMID: 15341765
- DOI: 10.1016/j.cub.2004.08.048
Item in Clipboard
Review
Tumor metastasis: a new twist on epithelial-mesenchymal transitions
Curr Biol.
.
Free article
Abstract
Epithelial-mesenchymal transitions are essential for normal embryonic development and for progression of non-invasive tumor cells into malignant, metastatic carcinomas. Twist, an important regulator of morphogenesis in the embryo, has recently been implicated in the onset of invasive behavior during tumor progression.
Similar articles
-
A Twist-Snail axis critical for TrkB-induced epithelial-mesenchymal transition-like transformation, anoikis resistance, and metastasis.Mol Cell Biol. 2009 Jul;29(13):3722-37. doi: 10.1128/MCB.01164-08. Epub 2009 May 4. Mol Cell Biol. 2009. PMID: 19414595 Free PMC article.
-
Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancer.Am J Pathol. 2002 Nov;161(5):1881-91. doi: 10.1016/S0002-9440(10)64464-1. Am J Pathol. 2002. PMID: 12414534 Free PMC article.
-
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis.Cell. 2004 Jun 25;117(7):927-39. doi: 10.1016/j.cell.2004.06.006. Cell. 2004. PMID: 15210113
-
Molecular requirements for epithelial-mesenchymal transition during tumor progression.Curr Opin Cell Biol. 2005 Oct;17(5):548-58. doi: 10.1016/j.ceb.2005.08.001. Curr Opin Cell Biol. 2005. PMID: 16098727 Review.
-
Epithelial-mesenchymal transitions: twist in development and metastasis.Cell. 2004 Aug 6;118(3):277-9. doi: 10.1016/j.cell.2004.07.011. Cell. 2004. PMID: 15294153 Review.
Cited by
-
Expression of SIP1 is strongly correlated with LDHA and shows a significantly poor outcome in gastric cancer.Tumour Biol. 2015 Sep;36(10):7521-30. doi: 10.1007/s13277-015-3470-7. Epub 2015 Apr 26. Tumour Biol. 2015. PMID: 25913622
-
Semaphorin-7a reverses the ERF-induced inhibition of EMT in Ras-dependent mouse mammary epithelial cells.Mol Biol Cell. 2012 Oct;23(19):3873-81. doi: 10.1091/mbc.E12-04-0276. Epub 2012 Aug 8. Mol Biol Cell. 2012. PMID: 22875994 Free PMC article.
-
Leptin-induced epithelial-mesenchymal transition in breast cancer cells requires β-catenin activation via Akt/GSK3- and MTA1/Wnt1 protein-dependent pathways.J Biol Chem. 2012 Mar 9;287(11):8598-612. doi: 10.1074/jbc.M111.322800. Epub 2012 Jan 23. J Biol Chem. 2012. PMID: 22270359 Free PMC article.
-
Expression of transcription factors snail, slug, and twist in human bladder carcinoma.J Exp Clin Cancer Res. 2010 Sep 1;29(1):119. doi: 10.1186/1756-9966-29-119. J Exp Clin Cancer Res. 2010. PMID: 20809941 Free PMC article.
-
Nanotechnology in metastatic cancer treatment: Current Achievements and Future Research Trends.J Cancer. 2019 Feb 7;10(6):1358-1369. doi: 10.7150/jca.28394. eCollection 2019. J Cancer. 2019. PMID: 31031845 Free PMC article. Review.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
