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Review
. 2004 Sep 7;14(17):R719-21.
doi: 10.1016/j.cub.2004.08.048.

Tumor metastasis: a new twist on epithelial-mesenchymal transitions

Ann E Vernon  1 , Carole LaBonne
Affiliations
Free article
Review

Tumor metastasis: a new twist on epithelial-mesenchymal transitions

Ann E Vernon et al. Curr Biol. .
Free article

Abstract

Epithelial-mesenchymal transitions are essential for normal embryonic development and for progression of non-invasive tumor cells into malignant, metastatic carcinomas. Twist, an important regulator of morphogenesis in the embryo, has recently been implicated in the onset of invasive behavior during tumor progression.

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