doi: 10.1016/j.bmcl.2004.07.036.
Pyrrolo[2,1-c][1,4]benzodiazepine-anthraquinone conjugates. Synthesis, DNA binding and cytotoxicity
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- PMID: 15341949
- DOI: 10.1016/j.bmcl.2004.07.036
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Pyrrolo[2,1-c][1,4]benzodiazepine-anthraquinone conjugates. Synthesis, DNA binding and cytotoxicity
Bioorg Med Chem Lett.
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Abstract
New pyrrolobenzodiazepine-anthraquinone hybrids have been designed and synthesized, found to effectively bind to DNA and also exhibit cytotoxicity against many cancer cell lines
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