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Clinical Trial
. 2004 Sep 1;94(5):659-62.
doi: 10.1016/j.amjcard.2004.05.037.

Comparative effects of carvedilol and amiodarone on conversion and recurrence rates of persistent atrial fibrillation

Emmanuel M Kanoupakis  1 , Emmanuel G Manios, Hercules E Mavrakis, Panos G Tzerakis, Helen K Mouloudi, Panos E Vardas
Affiliations
Clinical Trial

Comparative effects of carvedilol and amiodarone on conversion and recurrence rates of persistent atrial fibrillation

Emmanuel M Kanoupakis et al. Am J Cardiol. .

Abstract

Pretreatment with antiarrhythmic agents could improve cardioversion and recurrence rates in patients with persistent atrial fibrillation. In a prospective controlled trial, 145 patients were randomly assigned to treatment with carvedilol, amiodarone, or placebo for 4 weeks before electrical cardioversion. Although the 2 drugs had similar effects on cardioversion rates, amiodarone was superior in terms of sinus rhythm maintenance after conversion.

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