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Comment
. 2004 Jul;21(1):1-2.
doi: 10.1016/j.immuni.2004.07.003.

Mysterious origin of plasmacytoid dendritic cell precursors

Yui-Hsi Wang  1 , Yong-Jun Liu
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Free article
Comment

Mysterious origin of plasmacytoid dendritic cell precursors

Yui-Hsi Wang et al. Immunity. 2004 Jul.
Free article

Abstract

The origin of plasmacytoid dendritic cell precursors (pDC) has been controversial. This manuscript shows that CLP and CMP both can give rise to pDCs. pDCs derived from CMP express RAG gene products and show IgHD-J rearrangement, suggesting that pDC represent a unique lineage whose gene expression program shows substantial plasticity.

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