Bidirectional promoters regulate the monoallelically expressed Ly49 NK receptors
- PMID: 15345214
- DOI: 10.1016/j.immuni.2004.07.001
Bidirectional promoters regulate the monoallelically expressed Ly49 NK receptors
Abstract
Members of the Ly49 gene family of natural killer (NK) cell receptors in mice are expressed in seemingly stochastic combinations such that each NK cell expresses a handful of family members. A transcriptional switch appears to establish this interesting pattern of expression.
Comment on
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Identification of probabilistic transcriptional switches in the Ly49 gene cluster: a eukaryotic mechanism for selective gene activation.Immunity. 2004 Jul;21(1):55-66. doi: 10.1016/j.immuni.2004.06.005. Immunity. 2004. PMID: 15345220
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