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Case Reports
. 2004;32(4):375-7.
doi: 10.1515/JPM.2004.070.

Maternal anaphylaxis and fetal brain damage after intrapartum chemoprophylaxis

Alberto Berardi  1 , Katia Rossi, Francesca Cavalleri, Angela Simoni, Lorenzo Aguzzoli, Giuseppe Masellis, Fabrizio Ferrari
Affiliations
Case Reports

Maternal anaphylaxis and fetal brain damage after intrapartum chemoprophylaxis

Alberto Berardi et al. J Perinat Med. 2004.

Abstract

We report a case of maternal anaphylaxis following intrapartum chemoprophylaxis. The term fetus developed severe brain damage as a consequence of intrapartum asphyxia. The lesions resulted from maternal hypotension following anaphylaxis. We discuss the feto-maternal risks and the controversial treatment of such a condition. The increasing number of penicillin-treated parturients will result in further cases of maternal anaphylaxis than previously found.

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