Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1992 Jun;11(6):2219-28.
doi: 10.1002/j.1460-2075.1992.tb05281.x.

The prokaryotic enhancer binding protein NTRC has an ATPase activity which is phosphorylation and DNA dependent

S Austin  1 , R Dixon
Affiliations
Comparative Study

The prokaryotic enhancer binding protein NTRC has an ATPase activity which is phosphorylation and DNA dependent

S Austin et al. EMBO J. 1992 Jun.

Abstract

The prokaryotic activator protein NTRC binds to enhancer-like elements and activates transcription in response to nitrogen limitation by catalysing open complex formation by sigma 54 RNA polymerase holoenzyme. Formation of open complexes requires the phosphorylated form of NTRC and the reaction is ATP dependent. We find that NTRC has an ATPase activity which is activated by phosphorylation and is strongly stimulated by the presence of DNA containing specific NTRC binding sites.

PubMed Disclaimer

References

    1. EMBO J. 1989 Nov;8(11):3491-9 - PubMed
    1. Science. 1989 Sep 1;245(4921):952-8 - PubMed
    1. J Biol Chem. 1988 Aug 5;263(22):10761-5 - PubMed
    1. Proc Natl Acad Sci U S A. 1988 Dec;85(23):8919-23 - PubMed
    1. Proc Natl Acad Sci U S A. 1986 Aug;83(16):5909-13 - PubMed

Publication types

MeSH terms

LinkOut - more resources