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. 1997 Mar;8(3):157-61.
doi: 10.1023/a:1018523203667.

Bioactivity of sol-gel derived organically modified silicates: part i: in vitro examination

K Tsuru  1 , C Ohtsuki, A Osaka, T Iwamoto, J D Mackenzie
Affiliations

Bioactivity of sol-gel derived organically modified silicates: part i: in vitro examination

K Tsuru et al. J Mater Sci Mater Med. 1997 Mar.

Abstract

Bioactivity was investigated for several organically modified silicates (Ormosils) prepared through sol-gel processes. Ca(II)-free samples were biocompatible only, but Ca(II)containing samples were bioactive and deposited apatite during immersion in a simulated body fluid. The ease of silanol (Si-OH) group formation on the ormosils was considered a predominant factor controlling the bioactivity, while the effect of dissolved Ca(II) ions to increase the degree of supersaturation in the simulated body fluid is secondary.

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References

    1. J Biomed Mater Res. 1990 Jun;24(6):721-34 - PubMed

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