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. 1998 Dec;9(12):723-6.
doi: 10.1023/a:1008950902047.

Osteoinduction by calcium phosphate biomaterials

H Yuan  1 , Z Yang, Y Li, X Zhang, J D De Bruijn, K De Groot
Affiliations

Osteoinduction by calcium phosphate biomaterials

H Yuan et al. J Mater Sci Mater Med. 1998 Dec.

Abstract

Different materials were implanted in muscles of dogs to study the osteoinduction of calcium phosphate biomaterials. Bone formation was only seen in calcium phosphate biomaterials with micropores, and could be found in hydroxyapatite (HA) ceramic, tricalcium phosphate/hydroxyapatite ceramic (BCP), beta-TCP ceramic and calcium phosphate cement. The osteoinductive potential was different in different materials. The results indicate that osteoinduction can be a property of calcium phosphate biomaterials when they exhibit specific chemical and structural characteristics.

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