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Clinical Trial
. 2004 Oct 4;91(7):1236-8.
doi: 10.1038/sj.bjc.6602152.

The systemic inflammatory response, performance status and survival in patients undergoing alpha-interferon treatment for advanced renal cancer

Affiliations
Clinical Trial

The systemic inflammatory response, performance status and survival in patients undergoing alpha-interferon treatment for advanced renal cancer

E Bromwich et al. Br J Cancer. .

Abstract

The prognostic value of C-reactive protein, compared with ECOG performance status (ECOG-ps), in patients receiving alpha-interferon treatment for advanced renal cancer was assessed in 58 patients. In all, 55 patients died on follow-up. On multivariate analysis with ECOG-ps and C-reactive protein entered as covariates, only C-reactive protein was a significant independent predictor of survival (HR 2.03, 95% CI 1.09-3.80, P=0.026).

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Figures

Figure 1
Figure 1
(A) The relationship between C-reactive protein (⩽10 mgl−1 - - -, >10 mgl−1 __) and survival in patients receiving alpha-interferon treatment for advanced renal cancer. (B) The relationship between C-reactive protein (⩽50 mgl−1 - - -, >50 mgl−1 __) and survival in patients receiving alpha-interferon treatment for advanced renal cancer.

References

    1. Ando M, Ando Y, Hasegawa Y, Shimokata K, Minami H, Wakai K, Ohno Y, Sakai S (2001) Prognostic value of performance status assessed by patients themselves, nurses, and oncologists in advanced non-small cell lung cancer. Br J Cancer 85: 1634–1639 - PMC - PubMed
    1. Bennett M, Ryall N (2000) Using the modified Barthel index to estimate survival in cancer patients in hospice: observational study. BMJ 321(7273): 1381–1382 - PMC - PubMed
    1. Blay JY, Negrier S, Combaret V, Attali S, Goillot E, Merrouche Y, Mercatello A, Ravault A, Tourani JM, Moskovtchenko JF (1992) Serum level of interleukin 6 as a prognosis factor in metastatic renal cell carcinoma. Cancer Res 52: 3317–3322 - PubMed
    1. Forrest LM, McMillan DC, McArdle CS, Angerson WJ, Dunlop DJ (2003) Evaluation of cumulative prognostic scores based on the systemic inflammatory response in patients with inoperable non-small-cell lung cancer. Br J Cancer 89: 1028–1030 - PMC - PubMed
    1. Forrest LM, McMillan DC, McArdle CS, Angerson WJ, Dunlop DJ (2004) Comparison of an inflammation-based prognostic score (GPS) with performance status (ECOG) in patients receiving platinum-based chemotherapy for inoperable non-small-cell lung cancer. Br J Cancer 90: 1704–1706 - PMC - PubMed

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