Histological evidence of osseointegration in human retrieved fractured hydroxyapatite-coated screw-type implants: a case report

Abstract

Histological evidence of clinically successful dental implants is very rare. This case report presents histological evidence of osseointegration in human implants retrieved because of fractures at the connected portion between the abutments and fixtures due to a car accident. The duration of functional loading of the implants was 18 months. Two hydroxyapatite (HA)-coated screw-type implants were removed with part of the healthy bone from the mandibular left molar region. A block was prepared using cutting and grinding equipment to obtain a central section approximately 50 microm thick, which was stained with basic fuchsin and methylene blue. Histological examination revealed that the bone was dense and in close relation with the HA coating of the implants. The interspaces of each thread of the implant were filled with mineralized bone. Peri-implant soft tissue was not observed in the section. A high degree of osseointegration was noted, with a bone-to-implant contact of 87.5% (implant corresponding to tooth 36) and 97.4% (implant corresponding to tooth 37). The connection between the 30 and 50 microm HA coating and the metal was uniformly tight and constant. In conclusion, the histological evidence showed a high degree of osseointegration in two HA-coated screw-type dental implants retrieved after functional loading for 18 months.