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Case Reports
. 2004 Sep-Oct;62(5):595-6.

[Unexpected occurence of hemoglobin Athens-Georgia]

[Article in French]
Affiliations
  • PMID: 15355813
Free article
Case Reports

[Unexpected occurence of hemoglobin Athens-Georgia]

[Article in French]
R Granouillet et al. Ann Biol Clin (Paris). 2004 Sep-Oct.
Free article

Abstract

The following report concerned a 47 year old Caucasian diabetic patient. Routine HPLC of HbA1c (Variant II Biorad Laboratories - hemoglobin A1c program) resulted only in the evidence of HbF (1%) and increase in HbA1c (10%). Considering the presence of HbF a standard agarose gel electrophoresis of patient's hemoglobin was performed and revealed the presence of Hb Athens-Georgia. Consequently the occurrence of HbF during determination of HbA1c by HPLC should lead to perform a standard hemoglobin electrophoresis in order to explore an hidden, unsuspected and clinically silent occurrence of rare Hb variant or additional unsuspected increase in HbA2.

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