Review
doi: 10.1038/nrm1436.
Foot and mouth: podosomes, invadopodia and circular dorsal ruffles
Affiliations
- PMID: 15366708
- DOI: 10.1038/nrm1436
Item in Clipboard
Review
Foot and mouth: podosomes, invadopodia and circular dorsal ruffles
Nat Rev Mol Cell Biol.
2004 Aug.
Abstract
The plasma membrane of many motile cells undergoes highly regulated protrusions and invaginations that support the formation of podosomes, invadopodia and circular dorsal ruffles. Although they are similar in appearance and in their formation--which is mediated by a highly conserved actin-membrane apparatus--these transient surface membrane distortions are distinct. Their function is to help the cell as it migrates, attaches and invades.
Similar articles
-
The role of dynamin in the assembly and function of podosomes and invadopodia.Front Biosci. 2004 May 1;9:1944-53. doi: 10.2741/1348. Front Biosci. 2004. PMID: 14977600 Review.
-
Functions and regulation of circular dorsal ruffles.Mol Cell Biol. 2012 Nov;32(21):4246-57. doi: 10.1128/MCB.00551-12. Epub 2012 Aug 27. Mol Cell Biol. 2012. PMID: 22927640 Free PMC article. Review.
-
Cell biology. Podosomes and invadopodia help mobile cells step lively.Science. 2006 Jun 30;312(5782):1868-9. doi: 10.1126/science.312.5782.1868. Science. 2006. PMID: 16809506 No abstract available.
-
Palladin binds to Eps8 and enhances the formation of dorsal ruffles and podosomes in vascular smooth muscle cells.J Cell Sci. 2006 Aug 15;119(Pt 16):3316-24. doi: 10.1242/jcs.03076. Epub 2006 Jul 25. J Cell Sci. 2006. PMID: 16868024
-
Invadopodia and podosomes in tumor invasion.Eur J Cell Biol. 2006 Apr;85(3-4):213-8. doi: 10.1016/j.ejcb.2005.10.004. Epub 2005 Nov 8. Eur J Cell Biol. 2006. PMID: 16546563
Cited by
-
Emerging role of ILK and ELMO2 in the integration of adhesion and migration pathways.Cell Adh Migr. 2012 May-Jun;6(3):168-72. doi: 10.4161/cam.20399. Epub 2012 May 1. Cell Adh Migr. 2012. PMID: 22568984 Free PMC article.
-
Oktoberfest for adhesion structures.EMBO Rep. 2005 Oct;6(10):922-6. doi: 10.1038/sj.embor.7400526. EMBO Rep. 2005. PMID: 16170307 Free PMC article.
-
Dorsal ruffle microdomains potentiate Met receptor tyrosine kinase signaling and down-regulation.J Biol Chem. 2010 Aug 6;285(32):24956-67. doi: 10.1074/jbc.M110.127985. Epub 2010 Jun 7. J Biol Chem. 2010. PMID: 20529867 Free PMC article.
-
The primate-specific protein TBC1D3 is required for optimal macropinocytosis in a novel ARF6-dependent pathway.Mol Biol Cell. 2008 Apr;19(4):1304-16. doi: 10.1091/mbc.e07-06-0594. Epub 2008 Jan 16. Mol Biol Cell. 2008. PMID: 18199687 Free PMC article.
-
WAVE2- and microtubule-dependent formation of long protrusions and invasion of cancer cells cultured on three-dimensional extracellular matrices.Cancer Sci. 2008 Nov;99(11):2252-9. doi: 10.1111/j.1349-7006.2008.00927.x. Epub 2008 Sep 15. Cancer Sci. 2008. PMID: 18795939 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
