Ischemic stroke: "acidotoxicity" is a perpetrator
- PMID: 15369664
- DOI: 10.1016/j.cell.2004.09.004
Ischemic stroke: "acidotoxicity" is a perpetrator
Abstract
Ischemic stroke is a devastating neurological disease. The responsible mechanisms are not completely understood. In this issue of Cell, Xiong et al. (2004) elucidate a molecular mechanism by which acidosis damages the brain during ischemia.
Comment on
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Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels.Cell. 2004 Sep 17;118(6):687-98. doi: 10.1016/j.cell.2004.08.026. Cell. 2004. PMID: 15369669
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