Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2004 Sep 16;431(7006):371-8.
doi: 10.1038/nature02870.

Unlocking the potential of the human genome with RNA interference

Gregory J Hannon  1 , John J Rossi
Affiliations
Review

Unlocking the potential of the human genome with RNA interference

Gregory J Hannon et al. Nature. .

Abstract

The discovery of RNA interference (RNAi) may well be one of the transforming events in biology in the past decade. RNAi can result in gene silencing or even in the expulsion of sequences from the genome. Harnessed as an experimental tool, RNAi has revolutionized approaches to decoding gene function. It also has the potential to be exploited therapeutically, and clinical trials to test this possibility are already being planned.

PubMed Disclaimer

Publication types

Substances