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. 2004 Sep 15;94(6):817-20.
doi: 10.1016/j.amjcard.2004.05.072.

Usefulness of the peak velocity difference by tissue Doppler imaging technique as an effective predictor of response to cardiac resynchronization therapy

Dean Notabartolo  1 , John D Merlino, Andrew L Smith, David B DeLurgio, Fernando V Vera, Kirk A Easley, Randolph P Martin, Angel R León
Affiliations

Usefulness of the peak velocity difference by tissue Doppler imaging technique as an effective predictor of response to cardiac resynchronization therapy

Dean Notabartolo et al. Am J Cardiol. .

Abstract

Cardiac resynchronization therapy (CRT) improves symptoms and functional status in heart failure patients; however, current selection criteria need improvement. A novel tissue Doppler imaging parameter, the peak velocity difference (PVD), defined as the greatest difference in time to peak velocity between any of 6 left ventricular regions, may better select responders to CRT. Subjects were divided into 2 groups based on the PVD. Clinical and echocardiographic parameters significantly improved in subjects with dyssynchrony by the baseline PVD and had a better overall response to CRT.

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