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Case Reports
. 1992 Jan;31(1):160-4.
doi: 10.1097/00004583-199201000-00024.

Clozapine for the treatment of adolescents with schizophrenia

B Birmaher  1 , R Baker, S Kapur, H Quintana, R Ganguli
Affiliations
Case Reports

Clozapine for the treatment of adolescents with schizophrenia

B Birmaher et al. J Am Acad Child Adolesc Psychiatry. 1992 Jan.

Abstract

Despite recent reports that clozapine is useful for the treatment of chronic schizophrenics resistant to neuroleptics, no studies have been reported in adolescents with schizophrenia. Despite the risk of potentially fatal agranulocytosis, clozapine's use in adolescents may become important because of its lack of extrapyramidal side effects or association with tardive dyskinesia, and reports that suggest that schizophrenic adolescents resemble chronic adult schizophrenics. The authors report three successful trials of clozapine in adolescents with schizophrenia who did not respond to conventional neuroleptic treatment.

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Comment in

  • More on clozapine.
    Boxer GH, Davidson J. Boxer GH, et al. J Am Acad Child Adolesc Psychiatry. 1992 Sep;31(5):993. doi: 10.1097/00004583-199209000-00043. J Am Acad Child Adolesc Psychiatry. 1992. PMID: 1400143 No abstract available.
  • Clozapine for schizophrenia.
    Levkovitch Y, Kaysar N, Kronnenberg Y, Hagai H, Gaoni B. Levkovitch Y, et al. J Am Acad Child Adolesc Psychiatry. 1994 Mar-Apr;33(3):431. doi: 10.1097/00004583-199403000-00026. J Am Acad Child Adolesc Psychiatry. 1994. PMID: 8169194 No abstract available.
  • Clozapine for schizophrenia.
    Blanz B, Schmidt MH. Blanz B, et al. J Am Acad Child Adolesc Psychiatry. 1993 Jan;32(1):223-4. doi: 10.1097/00004583-199301000-00039. J Am Acad Child Adolesc Psychiatry. 1993. PMID: 8428878 No abstract available.

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