Protein degradation: recognition of ubiquitinylated substrates
- PMID: 15380085
- DOI: 10.1016/j.cub.2004.09.012
Protein degradation: recognition of ubiquitinylated substrates
Abstract
A cell-free system has been developed in budding yeast that provides direct evidence that the Dsk2/Dph1, Rad23/Rhp23 and Rpn10/Pus1 multi-ubiquitin-binding proteins, long implicated in substrate recognition and presentation to the 26S proteasome, actually fulfil such a role.
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