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Review
. 2004 Oct;14(5):499-505.
doi: 10.1016/j.gde.2004.07.005.

Choose your fate: artery, vein or lymphatic vessel?

Affiliations
Review

Choose your fate: artery, vein or lymphatic vessel?

Natasha L Harvey et al. Curr Opin Genet Dev. 2004 Oct.

Abstract

The specification of cell fate is integral to embryonic development. Recent research has identified several molecules that are involved in the development of the embryonic vasculature. Their combined actions are required for the specification and development of the arteries, veins and lymphatic vessels; vascular networks that are vital for embryonic and adult survival, and whose malfunction causes major pathological disorders. Recent discoveries have impacted our understanding of the embryonic origins of arterial, venous and lymphatic endothelial cells and the signals that mediate their navigation into mature, functional circulatory systems.

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