Review
doi: 10.1016/j.micinf.2004.05.026.
Cellular stress and signal transduction responses to human cytomegalovirus infection
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- PMID: 15380778
- DOI: 10.1016/j.micinf.2004.05.026
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Review
Cellular stress and signal transduction responses to human cytomegalovirus infection
Microbes Infect.
2004 Oct.
Free article
Abstract
Human cytomegalovirus (HCMV) receptor-ligand interactions and viral entry excite cellular responses such as receptor tyrosine kinase and mitogen-activated protein kinase signaling, cytoskeletal rearrangement, and the induction of transcription factors, prostaglandins, and cytokines. Bi-phasic stimulation of these pathways, excepting interferon, facilitates productive viral infection and likely contributes to viral pathogenesis.
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