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Review
. 2004 Oct;10(10 Suppl 2):S65-8.
doi: 10.1002/lt.20266.

Transplantation for hilar cholangiocarcinoma

Julie K Heimbach  1 , Michael G Haddock, Steven R Alberts, Scott L Nyberg, Michael B Ishitani, Charles B Rosen, Gregory J Gores
Affiliations
Free article
Review

Transplantation for hilar cholangiocarcinoma

Julie K Heimbach et al. Liver Transpl. 2004 Oct.
Free article

Abstract

1. Patients with primary sclerosing cholangitis (PSC) have a 8 to 12% risk of developing cholangiocarcinoma (CCA). 2. Cytologic techniques for aneuploidy such as digital image analysis and fluorescence in situ hybridization increase the detection rate for CCA. 3. Survival following resection for CCA is 20% to 40% at 5 years. 4. Survival following liver transplantation for unresectable, perihilar CCAs, mass lesion if present <3 cm, is greater than 80% at 5 years. 5. Patients with intrahepatic CCAs are not eligible for liver transplantation.

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