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. 2004 Oct;48(10):4054-5.
doi: 10.1128/AAC.48.10.4054-4055.2004.

Novel resistance-nodulation-cell division efflux system AdeDE in Acinetobacter genomic DNA group 3

Sze-Lok Chau  1 , Yiu-Wai Chu, Elizabeth T S Houang
Affiliations

Novel resistance-nodulation-cell division efflux system AdeDE in Acinetobacter genomic DNA group 3

Sze-Lok Chau et al. Antimicrob Agents Chemother. 2004 Oct.

Abstract

Resistance-nodulation-cell division type efflux pump AdeDE was identified in acinetobacters belonging to genomic DNA group 3. Inactivation of adeE showed that it may be responsible for reduced susceptibility to amikacin, ceftazidime, chloramphenicol, ciprofloxacin, erythromycin, ethidium bromide, meropenem, rifampin, and tetracycline. However, unlike what was found for other similar efflux systems, the open reading frame for the outer membrane component was not found downstream of the adeDE gene cluster.

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