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Review
. 2004 Sep 25;329(7468):724-8.
doi: 10.1136/bmj.329.7468.724.

Narcolepsy and excessive daytime sleepiness

Adam Zeman  1 , Tom Britton, Neil Douglas, Andrew Hansen, Jane Hicks, Robin Howard, Andrew Meredith, Ian Smith, Gregory Stores, Sue Wilson, Zenobia Zaiwalla
Affiliations
Review

Narcolepsy and excessive daytime sleepiness

Adam Zeman et al. BMJ. .
No abstract available

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Figures

Fig 1
Fig 1
Sleep stage recording from a normal polysomnogram. This record shows the normal cyclical alternation of sleep stages over the course of the night. Purple bars indicate rapid eye movement (REM) sleep. Note the decreasing amounts of slow wave sleep (SWS) and increasing amounts of REM sleep over the course of the night
Fig 2
Fig 2
Hypocretin system. The sleep-wake cycle is governed by a complex, multilevel neuronal system in the brain stem, thalamus, hypothalamus, and basal forebrain. Neurones in the hypothalamus producing hypocretin stabilise the activity of other key neuronal groups involved in the control of sleep and waking: these nuclei and their principal neurotransmitters are shown here in highly schematic fashion
See this image and copyright information in PMC

References

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    1. Stores G, Crawford C. Medical student education in sleep and its disorders. J R Coll Physicians Lond 1998;32: 149-53. - PMC - PubMed
    1. Britton T, Douglas N, Hansen A, Hicks J, Howard R, Meredith A, et al. Guidelines on the diagnosis and management of narcolepsy in adults and children. Ashtead: Taylor Patten Communications, 2002 (available at www.sleeping.org.uk or www.primarycaresleep.com).
    1. Overeem S, Mignot E, van Dijk JG, Lammers GJ. Narcolepsy: clinical features, new pathophysiologic insights and future perspectives. J Clin Neurophysiol 2001;18: 78-105. - PubMed
    1. Daniels E, King MA, Smith IE, Shneerson JM. Health-related quality of life in narcolepsy. J Sleep Res 2001;10: 75-81. - PubMed

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