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. 1950 Jan 20;33(3):243-64, pl.
doi: 10.1085/jgp.33.3.243.

Methyl green-pyronin; basis of selective staining of nucleic acids

N B KURNICK

Methyl green-pyronin; basis of selective staining of nucleic acids

N B KURNICK. J Gen Physiol. .

Abstract

1. Methyl green stains selectively highly polymerized desoxyribonucleic acid, and fails to stain, to any significant extent, depolymerized desoxyribonucleic acid and ribonucleic acid. 2. Pyronin stains preferentially low polymers of nucleic acid. 3. Triphenylmethane dyes with two amino groups appear to share the selectivity of methyl green. Those with three amino groups are not selective. 4. A stereochemical hypothesis is offered to account for these observations.

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References

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    1. Proc Natl Acad Sci U S A. 1948 Mar;34(3):75-80 - PubMed
    1. Biochem J. 1940 Jun;34(6):858-65 - PubMed