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Case Reports
. 1992 Mar;76(3):163-5.
doi: 10.1136/bjo.76.3.163.

Multifocal amelanotic conjunctival melanoma and acquired melanosis sine pigmento

A D Paridaens  1 , A C McCartney, J L Hungerford
Affiliations
Case Reports

Multifocal amelanotic conjunctival melanoma and acquired melanosis sine pigmento

A D Paridaens et al. Br J Ophthalmol. 1992 Mar.

Abstract

Clinical and histopathological features of four cases of multifocal amelanotic malignant melanoma of the conjunctiva in association with 'acquired melanosis sine pigmento' are reported. The absence of conjunctival pigmentation in this extremely rare combination of lesions prevented early diagnosis and clinical monitoring. As a result orbital exenteration was required in three cases. This multicentric non-pigmented variety of conjunctival malignant melanoma tends to present later than pigmented forms and may require exenteration of the orbit as a primary procedure.

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